Services

Diatec Monoclonals has over 25 years of experience in the production of monoclonal antibodies. Our customers range from academic research departments and startups to global diagnostics and pharmaceutical companies.

Antibody production

  • Mouse, rat, human, rabbit and CHO
  • Small & large scale, 25 mg to 100 g batches

Cell line optimisation

  • Recloning and optimisation of cell lines
  • Establishment of new cell lines

Quality control & assurance

  • SDS-PAGE, ELISA, GPC-HPLC and FLow
  • Certificate of Analysis with each batch

Downstream processing

  • Purification & vialing
  • Conjugation to enzymes or fluorecent probes

Cell line testing & incomming control

  • Mycoplasma test
  • Isotyping
  • Productivity check

Cell line storage & banking

  • Production of cell banks
  • Dual site storage in LN2

Tailor made solutions

We have both GMP and ISO 9001 approved production facilities. All productions can be customized to raw material, culturing media, and supplements. We deliver the antibodies in your choice of buffer, concentration, vialing, and labeling.

Experience

We have in-depth experience with a number of production platforms for monoclonal antibodies. The platform of choice will be driven by customer volume requirements, yield efficiency, and cost considerations.

Small scale productions

For small to intermediate scale productions, ranging from 25 mg to 5 g of purified antibodies, our platform of choice is Cell Line 1000 flasks. We have decades of experience producing high-quality results and high customer satisfaction with a range of diverse clones and culture media.

Large scale productions

For larger-scale productions, yielding 5 – 100 grams, we use an automated hollow fiber production platform. With these systems, we also have experience in delivering high-level customer satisfaction on both quality and value.

Other

We have, and continue to conduct, a number of Fusion projects for industrial clients, for which a significant number are used in commercial diagnostic kits, and others are currently in the commercialization process.

Many of our customers over the years have chosen us for Cell Banking, either primary or secondary, and we store thousands of ampoules in our strictly monitored systems.

We also provide a Recloning Service for customers, which in many cases has resulted in significant productivity increases, offering future production cost reductions.